Arrhythmogenic Disorders · Pathology

Which structural heart disease is most commonly associated with ventricular arrhythmias leading to sudden cardiac death?

  1. Congenital atrial septal defect
  2. Hypertrophic cardiomyopathy
  3. Mitral valve prolapse
  4. Patent ductus arteriosus
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Correct answer: Hypertrophic cardiomyopathy

Hypertrophic cardiomyopathy is a major cause of sudden cardiac death, particularly in young individuals. Myocyte disarray and fibrosis create an arrhythmogenic substrate that predisposes to ventricular tachyarrhythmias.

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