Arrhythmogenic Disorders · Pathology

Brugada syndrome is most commonly associated with mutations in which gene?

  1. SCN5A
  2. MYH7
  3. LMNA
  4. TNNT2
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Correct answer: SCN5A

Brugada syndrome is often linked to mutations in the SCN5A gene, which encodes a cardiac sodium channel. Dysfunction of this channel predisposes to life-threatening ventricular arrhythmias.

Difficulty: Medium Question 4 of 20

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