Electrolyte Imbalance in Renal Disease · NCLEX Exam

What is the most likely mechanism behind hyperkalemia in a patient with advanced chronic kidney disease (CKD)?

  1. Diuretics drive the kidneys to excrete excess potassium
  2. Reduced glomerular filtration limits potassium excretion
  3. Excessive dietary sodium intake drives potassium retention
  4. Potassium shifts intracellularly, raising the serum level
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Correct answer: Reduced glomerular filtration limits potassium excretion

In CKD reduced glomerular filtration and tubular excretion of potassium lead to hyperkalemia.

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