Neonatal Transition and Newborn Care · NCLEX Exam

The immediate first breath of a newborn primarily triggers which physiological change?

  1. Closure of the ductus venosus
  2. Increase in systemic vascular resistance
  3. Decrease in pulmonary vascular resistance
  4. Activation of fetal hemoglobin production
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Correct answer: Decrease in pulmonary vascular resistance

When the newborn takes the first breath, lung aeration causes pulmonary vessels to dilate and pulmonary vascular resistance (PVR) falls markedly.

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