Tumor Lysis Syndrome and Oncologic Emergencies · NCLEX Exam

What is the most critical nursing intervention for prevention of Tumor Lysis Syndrome?

  1. Restrict all oral fluids for 24 hours before therapy
  2. Give isotonic IV fluids before and after chemotherapy
  3. Hold all antihypertensive medications during therapy
  4. Administer high-dose IV potassium supplements
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Correct answer: Give isotonic IV fluids before and after chemotherapy

The critical intervention for TLS prevention is aggressive IV hydration with isotonic fluids before, during, and after therapy.

Difficulty: Easy Question 3 of 20

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