Immunotherapy and Targeted Therapy · NCLEX Exam

Which of the following best characterises a targeted therapy’s side-effect profile compared to chemotherapy?

  1. It reliably produces no side-effects of any kind
  2. It causes side-effects identical to those of chemotherapy
  3. It often causes fewer off-target effects but real target-related toxicities
  4. It causes only hair loss without any internal-organ effects
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Correct answer: It often causes fewer off-target effects but real target-related toxicities

Targeted therapies often spare many normal rapidly-dividing cells compared with chemotherapy, resulting in fewer general side-effects; however, they can still cause serious toxicities especially if the target is also present in normal tissue.

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