Immunotherapy and Targeted Therapy · NCLEX Exam

An example of an immune checkpoint inhibitor used in cancer is:

  1. A small-molecule drug that inhibits the BCR-ABL kinase
  2. A monoclonal antibody that blocks PD-1/PD-L1 signalling
  3. A small molecule that blocks VEGF receptor signalling
  4. A cytotoxic alkylating chemotherapy agent
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Correct answer: A monoclonal antibody that blocks PD-1/PD-L1 signalling

Immune checkpoint inhibitors block inhibitory receptors like PD-1/PD-L1 to enhance T-cell mediated immune activity against cancer.

Difficulty: Easy Question 4 of 20

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