Pathophysiology of Burn Injury · NCLEX Exam

In severe burn injury, why might hemoglobin and hematocrit readings be elevated in the first 12 hours?

  1. Because red blood cell production from marrow increases immediately
  2. Because intravascular fluid loss causes hemoconcentration of blood
  3. Because the burn itself rapidly induces a true anemia of injury
  4. Because circulating plasma volume increases dramatically early on
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Correct answer: Because intravascular fluid loss causes hemoconcentration of blood

Massive fluid shift out of the vascular compartment during burn injury causes plasma volume depletion and hemoconcentration, elevating hemoglobin and hematocrit early post-injury.

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