Osmoregulation and Water-Salt Balance · NCERT Biology

Which of the following is the most toxic nitrogenous waste requiring large amounts of water for its elimination?

  1. Urea
  2. Uric acid
  3. Ammonia
  4. Creatinine
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Correct answer: Ammonia

Ammonia is highly toxic and readily soluble in water, requiring approximately 300-500 ml of water for every gram of nitrogen removed. It is generally excreted by diffusion across body surfaces or gill surfaces in aquatic animals.

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