Human kidneys can produce urine nearly _____ times concentrated than the initial filtrate formed.
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Correct answer: 4
The counter-current mechanism involving the Loop of Henle and vasa recta helps maintain a concentration gradient in the medullary interstitium. This allows the human kidney to produce urine that is four times more concentrated (1200 mOsmol/L) than the initial filtrate (300 mOsmol/L).
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