Glomerulus · Histology

What is the primary function of the intraglomerular mesangial cells?

  1. Filtration of glucose and amino acids
  2. Production of renin in response to low blood pressure
  3. Acting as a glucose sensor for the nephron
  4. Structural support and phagocytic activity
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Correct answer: Structural support and phagocytic activity

Mesangial cells provide physical support to the capillary loops and possess contractile properties to regulate blood flow. They also act as phagocytes to clean the basement membrane of protein aggregates and immune complexes.

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