The 'filtration slits' located between the pedicels of podocytes are covered by a thin proteinaceous bridge called the:
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Correct answer: Slit diaphragm
The slit diaphragm is a specialized cell-cell junction composed of proteins like nephrin and podocin. It is the major size-selective filter that prevents the passage of molecules larger than albumin.
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More Glomerulus questions
- Which of the following describes the unique histological feature of glomerular endothelial cells?
- In a standard H&E stained section, the space between the visceral and parietal layers of Bowman's capsule is known as:
- The vascular pole of the glomerulus is characterized by the entrance and exit of which vessels?
- Which protein is the main structural component of the slit diaphragm, and its mutation often leads to congenital nephrotic syndrome?
- The parietal layer of Bowman's capsule is composed of which type of epithelium?
- Which component of the glomerular filtration barrier is the most important size-selective filter for large macromolecules?