Pulmonary Capillaries · Histology

What is the metabolic role of pulmonary capillaries regarding serotonin (5-HT)?

  1. They actively synthesize serotonin from tryptophan
  2. They remove and degrade circulating serotonin
  3. They secrete serotonin to induce bronchodilation
  4. They have no interaction with serotonin
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Correct answer: They remove and degrade circulating serotonin

Pulmonary endothelial cells are highly active metabolically and can remove or inactivate various circulating substances. Serotonin is one such biogenic amine that is efficiently cleared from the blood as it passes through the lungs.

Difficulty: Medium Question 7 of 20

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