Nerve Regeneration · Histology

Transneuronal (transsynaptic) degeneration refers to:

  1. The death of a neuron after its axon is cut
  2. Degeneration of a synaptically connected neuron
  3. The transdifferentiation of a neuron into a glial cell
  4. Regeneration that occurs across a synapse
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Correct answer: Degeneration of a synaptically connected neuron

Nerve injury can sometimes affect the health of the neurons it communicates with. Transneuronal degeneration is the atrophy or death of a neuron resulting from the loss of its synaptic input (anterograde) or output (retrograde).

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