Simple Columnar Epithelium · Histology

Which junctional structure prevents the leakage of digestive enzymes between the lateral membranes of simple columnar cells in the gut?

  1. Gap junctions
  2. Hemidesmosomes
  3. Macula adherens (Desmosomes)
  4. Zonula occludens
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Correct answer: Zonula occludens

Zonula occludens form a seal near the apical pole of the cells. This barrier prevents the paracellular transport of large molecules and maintains the distinct chemical environments of the lumen and the intercellular space.

Difficulty: Medium Question 8 of 20

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