Simple Columnar Epithelium · Histology

Under a light microscope, the nuclei of simple columnar cells typically appear:

  1. Perfectly spherical and central
  2. Flattened and pressed against the apical membrane
  3. Oval or elongated and oriented vertically
  4. Multi-lobed and irregularly shaped
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Correct answer: Oval or elongated and oriented vertically

Nuclei in columnar cells reflect the shape of the cell itself. They are elongated along the long axis of the cell and are usually found in a consistent row near the basal surface.

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