Pseudostratified Epithelium · Histology

What is the result of Kartagener syndrome on pseudostratified ciliated epithelium?

  1. Excessive mucus production
  2. Loss of the basement membrane
  3. Transformation into simple squamous epithelium
  4. Immotile cilia due to a lack of dynein arms
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Correct answer: Immotile cilia due to a lack of dynein arms

Kartagener syndrome (Primary Ciliary Dyskinesia) is a genetic disorder where the dynein arms are missing or defective. This leads to chronic respiratory infections because the mucociliary escalator cannot function.

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