Pseudostratified Epithelium · Histology

What is the defining histological characteristic that makes an epithelium 'pseudostratified'?

  1. Multiple layers of cells where only the top layer is columnar
  2. A single layer of cells where all cells reach the apical surface but not the basement membrane
  3. A layer where all cells contact the basement membrane but not all reach the apical surface
  4. Two distinct layers of cells that both contact the basement membrane
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Correct answer: A layer where all cells contact the basement membrane but not all reach the apical surface

In pseudostratified epithelium, every cell is anchored to the basement membrane. Because the cells vary in height and their nuclei are located at different levels, it creates the optical illusion of stratification.

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