Liver Histology · Histology

The 'Space of Disse' (perisinusoidal space) is located between which two structures?

  1. Two adjacent hepatocytes
  2. The bile canaliculus and the bile duct
  3. The hepatic artery and the portal vein
  4. Sinusoidal endothelium and hepatocytes
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Correct answer: Sinusoidal endothelium and hepatocytes

The Space of Disse is the narrow gap between the fenestrated endothelial cells of the sinusoid and the microvilli-covered surface of the hepatocytes. It is the primary site of metabolic exchange between the blood and liver cells.

Difficulty: Medium Question 4 of 20

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