Liver Histology · Histology

Which histological feature characterizes the hepatic sinusoids?

  1. Discontinuous endothelium with fenestrae
  2. Continuous basement membrane and tight junctions
  3. Thick smooth muscle layer for contraction
  4. Lined by simple columnar epithelium
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Correct answer: Discontinuous endothelium with fenestrae

Hepatic sinusoids are specialized capillaries with a highly permeable, discontinuous endothelium. This allows plasma (but not blood cells) to directly contact hepatocytes in the Space of Disse for efficient nutrient processing.

Difficulty: Medium Question 8 of 20

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