Gastric Glands · Histology

Which hormone is secreted by D-cells in the gastric glands to inhibit the secretion of gastrin and HCl?

  1. Secretin
  2. Somatostatin
  3. Cholecystokinin
  4. Ghrelin
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Correct answer: Somatostatin

Somatostatin is a major inhibitory hormone produced by D-cells. It acts in a paracrine fashion to suppress the activity of G-cells and parietal cells, providing a negative feedback loop for acid control.

Difficulty: Medium Question 12 of 20

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