Gastric Glands · Histology

The basophilia seen in the basal region of Chief cells is due to the presence of:

  1. Dense-core secretory granules
  2. Mitochondria
  3. Rough endoplasmic reticulum
  4. Phagosomes
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Correct answer: Rough endoplasmic reticulum

Like most cells specialized for protein secretion, Chief cells have an abundance of rough ER in their basal cytoplasm. The ribosomes associated with the ER bind basic dyes, resulting in a purple/blue appearance.

Difficulty: Medium Question 16 of 20

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