Cartilage Degeneration · Histology

Which molecule in cartilage matrix attracts water and is reduced during degeneration?

  1. Type II collagen
  2. Proteoglycans
  3. Tropocollagen
  4. Fibronectin
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Correct answer: Proteoglycans

Proteoglycans attract and retain water within the cartilage matrix. Their reduction decreases cartilage elasticity and shock absorption.

Difficulty: Medium Question 7 of 20

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