Which enzyme group is mainly responsible for degrading cartilage extracellular matrix?
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Correct answer: Proteases
Proteases such as matrix metalloproteinases degrade collagen and proteoglycans in cartilage. Their increased activity contributes to cartilage degeneration.
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More Cartilage Degeneration questions
- Which joint component becomes exposed when articular cartilage degenerates severely?
- Which factor commonly accelerates cartilage degeneration?
- Which cartilage zone is first affected in early degeneration of articular cartilage?
- Which type of cartilage is most commonly affected by degenerative joint diseases?
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- Which imaging or histological sign indicates progressive cartilage loss?