Cartilage Degeneration · Histology

Which histological observation may indicate late-stage cartilage degeneration?

  1. Smooth cartilage surface
  2. Increased chondroblastic activity
  3. Thickened perichondrium
  4. Formation of cracks and fissures
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Correct answer: Formation of cracks and fissures

Cracks and fissures in cartilage indicate severe degeneration. These structural defects compromise joint movement and increase friction.

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