Osteoblasts · Histology

Which vitamin is essential for the synthesis of osteocalcin by osteoblasts?

  1. Vitamin K
  2. Vitamin A
  3. Vitamin E
  4. Vitamin B12
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Correct answer: Vitamin K

Vitamin K is a cofactor for the carboxylation of glutamic acid residues in osteocalcin. This modification is necessary for the protein to bind calcium and participate in the mineralization of the bone matrix.

Difficulty: Medium Question 18 of 20

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