Osteoblasts · Histology

What is the primary effect of intermittent low doses of Parathyroid Hormone (PTH) on osteoblasts?

  1. It stimulates osteoblast activity and bone formation.
  2. It triggers immediate cell death.
  3. It causes them to dedifferentiate and revert to fibroblasts.
  4. It has no effect on osteoblasts.
Show answer and explanation

Correct answer: It stimulates osteoblast activity and bone formation.

While chronic high levels of PTH promote bone resorption, intermittent low doses actually have an anabolic effect. They stimulate osteoblast survival and activity, which is a mechanism used in some treatments for osteoporosis.

Difficulty: Medium Question 19 of 20

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