Blood Disorders · Histology

Howell-Jolly bodies are small nuclear remnants in erythrocytes that are typically removed by which organ?

  1. Liver
  2. Kidney
  3. Spleen
  4. Thymus
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Correct answer: Spleen

Under normal conditions, the spleen removes these nuclear remnants through a process called pitting. Their presence in a peripheral smear usually indicates splenic dysfunction or that the spleen has been surgically removed (asplenia).

Difficulty: Medium Question 19 of 20

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