Anaphylaxis and Allergic Reactions · CDA

If the first dose of epinephrine does not reverse anaphylaxis symptoms in a dental office, what is the recommended next action?

  1. Give an antihistamine and then wait a full 30 minutes for a response
  2. Administer a second IM dose of epinephrine after 5 to 15 minutes
  3. Begin chest compressions immediately even though the patient is conscious
  4. Switch to oral corticosteroids as the mainstay of continued treatment
Show answer and explanation

Correct answer: Administer a second IM dose of epinephrine after 5 to 15 minutes

If symptoms persist, a second IM dose of epinephrine may be given after 5–15 minutes — repeated dosing is often needed, especially in biphasic or persistent reactions.

Difficulty: Medium Question 5 of 21

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