Genetics

Extra-Chromosomal Inheritance Practice Questions

20 free Extra-Chromosomal Inheritance practice questions for the Zoology. Tap an option to answer — you get instant feedback, the correct answer, and a detailed explanation for every question.

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Question 1 of 20 Medium

Which type of inheritance is characteristic of mitochondrial DNA transmission?

  1. A Paternal inheritance
  2. B Biparental inheritance
  3. C Autosomal inheritance
  4. D Maternal inheritance

Correct answer: Maternal inheritance

Mitochondrial DNA is inherited almost exclusively from the mother because the egg contributes most of the cytoplasm. Sperm mitochondria are typically degraded after fertilization.

Question 2 of 20 Medium

Which organelle is primarily responsible for extra-chromosomal inheritance in animal cells?

  1. A Nucleus
  2. B Golgi apparatus
  3. C Lysosome
  4. D Mitochondria

Correct answer: Mitochondria

Mitochondria contain their own DNA separate from nuclear DNA. This DNA is responsible for extra-chromosomal inheritance in animal cells.

Question 3 of 20 Medium

Which feature distinguishes mitochondrial DNA from nuclear DNA?

  1. A Linear structure
  2. B Histone association
  3. C Circular structure
  4. D Located in chromosomes

Correct answer: Circular structure

Mitochondrial DNA is circular and resembles bacterial DNA. It does not associate with histones like nuclear DNA does.

Question 4 of 20 Medium

Which condition demonstrates mitochondrial inheritance in humans?

  1. A Charcot-Marie-Tooth disease type 1A
  2. B Sickle cell anemia
  3. C Leber's hereditary optic neuropathy
  4. D Klinefelter syndrome

Correct answer: Leber's hereditary optic neuropathy

Leber's hereditary optic neuropathy is caused by mutations in mitochondrial DNA. It is inherited maternally and affects vision.

Question 5 of 20 Medium

What is the term for the presence of both normal and mutated mitochondrial DNA within a cell?

  1. A Homoplasmy
  2. B Polyploidy
  3. C Uniparental disomy
  4. D Heteroplasmy

Correct answer: Heteroplasmy

Heteroplasmy refers to the coexistence of normal and mutated mitochondrial DNA within the same cell. This can influence disease severity.

Question 6 of 20 Medium

Which process explains the origin of mitochondria and chloroplasts?

  1. A Gene duplication
  2. B Mutation theory
  3. C Endosymbiotic theory
  4. D Chromosomal theory of inheritance

Correct answer: Endosymbiotic theory

The endosymbiotic theory suggests that mitochondria and chloroplasts originated from free-living bacteria engulfed by ancestral eukaryotic cells. Their own DNA supports this idea.

Question 7 of 20 Medium

Chloroplast DNA is primarily inherited through which parent in most plants?

  1. A Paternal parent
  2. B Both parents equally
  3. C Maternal parent
  4. D Random inheritance

Correct answer: Maternal parent

In most plants, chloroplast DNA is inherited maternally through the egg cell. Pollen typically contributes little cytoplasm.

Question 8 of 20 Medium

Which statement best describes cytoplasmic inheritance?

  1. A Inheritance via organelles outside the nucleus
  2. B Inheritance via nuclear genes only
  3. C Inheritance based on epigenetic gene modifications
  4. D Inheritance via protein synthesis

Correct answer: Inheritance via organelles outside the nucleus

Cytoplasmic inheritance involves genes located outside the nucleus, mainly in mitochondria and chloroplasts. These genes are passed through cytoplasmic components.

Question 9 of 20 Medium

Which trait in plants is often associated with chloroplast inheritance?

  1. A Leaf variegation
  2. B Flower color
  3. C Seed size
  4. D Stem thickness variation

Correct answer: Leaf variegation

Leaf variegation is often controlled by chloroplast genes. Mutations in chloroplast DNA can lead to patches of green and white tissue.

Question 10 of 20 Medium

Why is mitochondrial inheritance considered non-Mendelian?

  1. A It follows dominant-recessive patterns
  2. B It involves independent assortment
  3. C It does not follow Mendel's laws
  4. D It involves crossing over

Correct answer: It does not follow Mendel's laws

Mitochondrial inheritance does not follow Mendel's laws because it is transmitted through cytoplasm rather than nuclear genes. It shows maternal inheritance patterns.

Question 11 of 20 Medium

Which of the following is a characteristic of chloroplast DNA?

  1. A Circular and small
  2. B Linear and large
  3. C Double-stranded RNA
  4. D Protein-based genome

Correct answer: Circular and small

Chloroplast DNA is circular and relatively small, similar to bacterial genomes. It supports the endosymbiotic origin of chloroplasts.

Question 12 of 20 Medium

What is the main reason paternal mitochondria are not inherited?

  1. A They are inactive
  2. B They lack DNA
  3. C They are selectively degraded
  4. D They are diluted out during embryonic development

Correct answer: They are selectively degraded

Paternal mitochondria are actively degraded after fertilization. This ensures maternal inheritance of mitochondrial DNA.

Question 13 of 20 Medium

Which organelle is involved in photosynthesis and shows extra-chromosomal inheritance?

  1. A Chloroplast
  2. B Mitochondria
  3. C Endoplasmic reticulum
  4. D Ribosome

Correct answer: Chloroplast

Chloroplasts are responsible for photosynthesis and contain their own DNA. This DNA is inherited independently of nuclear DNA.

Question 14 of 20 Medium

Which term describes identical mitochondrial DNA copies within a cell?

  1. A Homoplasmy
  2. B Heteroplasmy
  3. C Diploidy
  4. D Polyteny

Correct answer: Homoplasmy

Homoplasmy refers to the presence of identical mitochondrial DNA copies in a cell. This contrasts with heteroplasmy, where variations exist.

Question 15 of 20 Medium

Which experimental evidence supports cytoplasmic inheritance?

  1. A Reciprocal crosses showing different results
  2. B Punnett square analysis
  3. C Chromosomal mapping using linkage analysis techniques
  4. D Protein synthesis experiments

Correct answer: Reciprocal crosses showing different results

Reciprocal crosses showing different outcomes indicate cytoplasmic inheritance. This suggests that traits are inherited through cytoplasmic components rather than nuclear genes.

Question 16 of 20 Medium

Which genome is smaller and encodes fewer proteins compared to nuclear DNA?

  1. A Mitochondrial genome
  2. B Nuclear genome
  3. C Plasmid genome
  4. D Bacteriophage genome

Correct answer: Mitochondrial genome

The mitochondrial genome is much smaller than the nuclear genome and encodes only a limited number of proteins. Most mitochondrial proteins are encoded by nuclear genes.

Question 17 of 20 Medium

Which inheritance pattern is shown when only offspring of affected mothers are affected?

  1. A Autosomal dominant
  2. B X-linked
  3. C Mitochondrial
  4. D Y-linked

Correct answer: Mitochondrial

Mitochondrial inheritance shows this pattern because mitochondria are transmitted from mothers. Affected fathers do not pass the trait to offspring.

Question 18 of 20 Medium

Which structure contains genes responsible for ATP production in cells?

  1. A Nucleus
  2. B Mitochondria
  3. C Chloroplast
  4. D Golgi apparatus

Correct answer: Mitochondria

Mitochondria contain genes that code for proteins involved in oxidative phosphorylation and ATP production. These genes are part of mitochondrial DNA.

Question 19 of 20 Medium

Which concept explains why chloroplasts divide independently of the nucleus?

  1. A Linked gene inheritance
  2. B Autonomous replication
  3. C Chromosomal crossing over
  4. D Elevated mutation rate

Correct answer: Autonomous replication

Chloroplasts replicate autonomously using their own DNA. This autonomy supports their role in extra-chromosomal inheritance.

Question 20 of 20 Medium

Which of the following best describes the genetic origin of chloroplasts?

  1. A Derived from mitochondria
  2. B Derived from cyanobacteria
  3. C Derived from the nucleus
  4. D Derived from RNA viruses

Correct answer: Derived from cyanobacteria

Chloroplasts are believed to have evolved from cyanobacteria through endosymbiosis. Their DNA and structure resemble those of these bacteria.

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