Cell Biology

Prokaryotic and Eukaryotic Cells Practice Questions

20 free Prokaryotic and Eukaryotic Cells practice questions for the Zoology. Tap an option to answer — you get instant feedback, the correct answer, and a detailed explanation for every question.

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Question 1 of 20 Medium

Which feature is common to both prokaryotic and eukaryotic cells?

  1. A Membrane-bound nucleus
  2. B 80S ribosomes
  3. C Plasma membrane
  4. D Mitochondria

Correct answer: Plasma membrane

All living cells possess a plasma membrane that encloses the cytoplasm and regulates exchange with the environment. Prokaryotes lack membrane-bound organelles like the nucleus and mitochondria, which are found only in eukaryotes.

Question 2 of 20 Medium

The genetic material in a typical prokaryotic cell is best described as:

  1. A Linear DNA enclosed within a membrane-bound nucleus
  2. B Circular DNA located in the nucleoid region
  3. C Multiple linear chromosomes associated with histones
  4. D RNA molecules dispersed throughout the cytoplasm

Correct answer: Circular DNA located in the nucleoid region

Prokaryotic DNA is usually circular and lies in a region called the nucleoid, not surrounded by a nuclear membrane. Histone-associated linear chromosomes are characteristic of eukaryotic cells.

Question 3 of 20 Medium

Which organelle is responsible for energy production in eukaryotic cells but is absent in prokaryotes?

  1. A Ribosome
  2. B Chloroplast
  3. C Mitochondrion
  4. D Golgi apparatus

Correct answer: Mitochondrion

Mitochondria carry out aerobic respiration and ATP synthesis in eukaryotic cells. Prokaryotes lack mitochondria and perform respiratory processes at the plasma membrane.

Question 4 of 20 Medium

Which statement correctly distinguishes eukaryotic cells from prokaryotic cells?

  1. A Eukaryotic cells completely lack ribosomes of any kind
  2. B Eukaryotic cells contain membrane-bound organelles
  3. C Eukaryotic cells are exclusively unicellular organisms
  4. D Eukaryotic cells carry only circular DNA like prokaryotes

Correct answer: Eukaryotic cells contain membrane-bound organelles

A defining feature of eukaryotic cells is the presence of membrane-bound organelles such as the nucleus, mitochondria, and endoplasmic reticulum. Prokaryotic cells do not have such compartmentalization.

Question 5 of 20 Medium

Which structure is present in prokaryotic cells but absent in animal cells?

  1. A Plasma membrane
  2. B Rigid cell wall surrounding the cell
  3. C Ribosomes for protein synthesis
  4. D Cytoplasm as cellular medium

Correct answer: Rigid cell wall surrounding the cell

Most prokaryotes possess a rigid cell wall that provides shape and protection. Animal cells lack a cell wall and rely on the plasma membrane and cytoskeleton for structural support.

Question 6 of 20 Medium

The ribosomes found in prokaryotic cells are typically:

  1. A 80S and attached to endoplasmic reticulum
  2. B 70S and free in the cytoplasm
  3. C 90S and membrane-bound
  4. D 60S and located in the nucleus

Correct answer: 70S and free in the cytoplasm

Prokaryotic ribosomes are smaller 70S ribosomes that float freely in the cytoplasm. Eukaryotic cells mainly contain larger 80S ribosomes in the cytosol and on the rough endoplasmic reticulum.

Question 7 of 20 Medium

Which of the following best describes the nucleus of a eukaryotic cell?

  1. A A region without a membrane that holds genetic material
  2. B A membrane-bound organelle containing genetic material
  3. C A structure that forms only during cell division
  4. D An organelle that participates in protein synthesis

Correct answer: A membrane-bound organelle containing genetic material

The eukaryotic nucleus is enclosed by a double-layered nuclear membrane and houses the cell's DNA. This compartmentalization is absent in prokaryotic cells.

Question 8 of 20 Medium

Which cellular process occurs in both prokaryotic and eukaryotic cells?

  1. A Photosynthesis in chloroplasts
  2. B Oxidative phosphorylation in mitochondria
  3. C Protein synthesis by ribosomes
  4. D Nuclear division through mitosis

Correct answer: Protein synthesis by ribosomes

Protein synthesis is a universal cellular process carried out by ribosomes in all cells. Structures like mitochondria, chloroplasts, and the mitotic apparatus are exclusive to eukaryotes.

Question 9 of 20 Medium

Which feature allows eukaryotic cells to be larger and more complex than prokaryotic cells?

  1. A Presence of plasmids in the cytoplasm
  2. B Absence of a rigid cell wall
  3. C Internal compartmentalization by membranes
  4. D Circular arrangement of chromosomal DNA

Correct answer: Internal compartmentalization by membranes

Eukaryotic cells contain membrane-bound compartments that separate and regulate different metabolic activities. This organization supports greater size and functional complexity compared to prokaryotes.

Question 10 of 20 Medium

Which of the following correctly matches a cell type with its typical example?

  1. A Prokaryotic cell – Amoeba (unicellular protist)
  2. B Eukaryotic cell – Bacterium (single-celled organism)
  3. C Prokaryotic cell – Escherichia coli
  4. D Eukaryotic cell – Mycoplasma (wall-less bacterium)

Correct answer: Prokaryotic cell – Escherichia coli

Escherichia coli is a bacterium and therefore a prokaryotic cell. Amoeba is a unicellular eukaryote, while Mycoplasma is actually a prokaryote lacking a cell wall.

Question 11 of 20 Medium

Which cellular component is involved in lipid synthesis and is found only in eukaryotic cells?

  1. A Smooth endoplasmic reticulum
  2. B Ribosome for protein assembly
  3. C Plasma membrane boundary layer
  4. D Nucleoid DNA-containing region

Correct answer: Smooth endoplasmic reticulum

The smooth endoplasmic reticulum synthesizes lipids and is a membrane-bound organelle found only in eukaryotic cells. Prokaryotes lack endoplasmic reticulum.

Question 12 of 20 Medium

In prokaryotic cells, the respiratory enzymes are mainly located in the:

  1. A Mitochondria (absent in prokaryotes)
  2. B Outer cell wall layer
  3. C Plasma membrane
  4. D Nucleoid chromosomal region

Correct answer: Plasma membrane

Prokaryotes lack mitochondria, so respiratory enzymes are embedded in the plasma membrane. This membrane carries out functions analogous to mitochondrial membranes in eukaryotes.

Question 13 of 20 Medium

Which statement about cell size is correct?

  1. A Prokaryotic cells are generally larger than eukaryotic cells
  2. B Both prokaryotic and eukaryotic cells are the same size
  3. C Eukaryotic cells are generally larger than prokaryotic cells
  4. D Cell size does not depend on cellular organization

Correct answer: Eukaryotic cells are generally larger than prokaryotic cells

Eukaryotic cells are typically larger due to internal compartmentalization and cytoskeletal support. Prokaryotic cells are usually much smaller and simpler in structure.

Question 14 of 20 Medium

Which structure helps in the attachment of bacterial cells to surfaces?

  1. A Cilia
  2. B Pili (hair-like appendages)
  3. C Flagella
  4. D Centrioles

Correct answer: Pili (hair-like appendages)

Pili are hair-like appendages found in many prokaryotes that facilitate attachment to surfaces and conjugation between bacterial cells. Cilia and centrioles are eukaryotic structures not found in bacteria.

Question 15 of 20 Medium

Which of the following is a true statement regarding DNA packaging?

  1. A Prokaryotic DNA is associated with histones like eukaryotes
  2. B Eukaryotic DNA is not associated with proteins
  3. C Eukaryotic DNA is packaged with histone proteins
  4. D Prokaryotic DNA is enclosed in a nuclear envelope

Correct answer: Eukaryotic DNA is packaged with histone proteins

In eukaryotes, DNA is tightly packaged with histone proteins to form chromatin. Prokaryotic DNA generally lacks histones and is not enclosed by a nuclear membrane.

Question 16 of 20 Medium

Which organelle modifies and packages proteins in eukaryotic cells?

  1. A Rough endoplasmic reticulum
  2. B Golgi apparatus
  3. C Lysosome for waste digestion
  4. D Mitochondrion

Correct answer: Golgi apparatus

The Golgi apparatus modifies, sorts, and packages proteins received from the endoplasmic reticulum. This organelle is absent in prokaryotic cells.

Question 17 of 20 Medium

Which feature is characteristic of all living cells?

  1. A Presence of a nucleus
  2. B Capacity to carry out metabolism
  3. C Membrane-bound organelles
  4. D Cell wall made of cellulose

Correct answer: Capacity to carry out metabolism

All living cells perform metabolic activities essential for survival. Features like nuclei, membrane-bound organelles, or cellulose cell walls are not universal to all cells.

Question 18 of 20 Medium

Which structure is involved in maintaining cell shape in both prokaryotes and eukaryotes?

  1. A Cell wall
  2. B Cytoskeleton
  3. C Plasma membrane
  4. D Nuclear envelope

Correct answer: Plasma membrane

The plasma membrane helps maintain the integrity and basic shape of all cells. While cell walls and cytoskeletons vary among organisms, the plasma membrane is universal.

Question 19 of 20 Medium

Which of the following correctly differentiates prokaryotic transcription from eukaryotic transcription?

  1. A Prokaryotic transcription occurs in the nucleus
  2. B Eukaryotic transcription occurs in the cytoplasm
  3. C Prokaryotic transcription and translation occur simultaneously
  4. D Eukaryotic transcription lacks RNA polymerase

Correct answer: Prokaryotic transcription and translation occur simultaneously

In prokaryotes, transcription and translation occur simultaneously in the cytoplasm. In eukaryotes, transcription occurs in the nucleus and is separated from translation in the cytoplasm.

Question 20 of 20 Medium

Which of the following pairs is correctly matched?

  1. A Prokaryote – membrane-bound nucleus
  2. B Eukaryote – nucleoid region
  3. C Prokaryote – smaller 70S ribosomes
  4. D Eukaryote – absence of organelles

Correct answer: Prokaryote – smaller 70S ribosomes

Prokaryotic cells contain 70S ribosomes, which are smaller than the 80S ribosomes of eukaryotes. The other options incorrectly assign features between the two cell types.

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