Carbohydrates and Glycoconjugates · Zoology

On the red blood cell surface, ABO blood group antigens are carried on which type of molecule?

  1. Glucose molecules only
  2. Fructose molecules only
  3. Membrane cholesterol and phospholipids
  4. Glycoproteins and glycolipids
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Correct answer: Glycoproteins and glycolipids

ABO blood group antigens are oligosaccharide chains attached to both glycoproteins and glycolipids on the red cell membrane; the immunodominant terminal sugars (for example N-acetylgalactosamine for the A antigen) determine specificity.

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