Nervous System: Neuron, Synapse, Reflexes · Zoology

What is the role of Acetylcholinesterase in synaptic transmission?

  1. To synthesize acetylcholine from choline and acetyl-CoA
  2. To transport acetylcholine into synaptic vesicles
  3. To break down acetylcholine in the synaptic cleft to terminate the signal
  4. To act as the primary receptor for acetylcholine on the postsynaptic membrane
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Correct answer: To break down acetylcholine in the synaptic cleft to terminate the signal

Acetylcholinesterase is an enzyme that rapidly hydrolyzes acetylcholine. This prevents continuous stimulation of the postsynaptic cell and allows the synapse to be ready for the next signal.

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