Which intracellular buffer system contributes significantly to pH regulation inside cells?
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Correct answer: Phosphate and protein buffers
Inside cells, phosphate and proteins (with ionizable side chains) serve as major intracellular buffers to resist changes in intracellular H⁺ concentration.
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More Acid-base homeostasis questions
- Which of the following best describes metabolic acidosis on arterial blood gas analysis?
- Why are small changes in plasma H⁺ concentration physiologically significant even though absolute H⁺ concentration is tiny (≈ 40 nmol/L)?
- Which of the following represents a primary disturbance in respiratory acidosis?
- Which renal tubular cell type is primarily responsible for H⁺ secretion during chronic acid–base regulation?
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