Which hemodynamic disorder can lead to hemosiderin-laden macrophages (so-called 'heart failure cells') in the lungs on histology?
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Correct answer: Chronic passive pulmonary congestion
Chronic passive pulmonary congestion causes red cell extravasation and breakdown; alveolar macrophages ingest hemoglobin, degrading it to hemosiderin — producing 'heart-failure cells'.
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