Autopsy and Gross Pathology · USMLE Step 1

During gross pathology examination, which finding suggests a malignancy rather than a benign lesion?

  1. Well-circumscribed with a uniform cut-surface
  2. Soft, uniformly homogeneous consistency
  3. Infiltrative borders with necrosis
  4. Small, well-defined lesion under 1 cm
Show answer and explanation

Correct answer: Infiltrative borders with necrosis

Malignant lesions typically show irregular, infiltrative borders with areas of necrosis and hemorrhage and a variegated cut surface, unlike well-circumscribed benign lesions.

Difficulty: Medium Question 9 of 20

Practice all 20 Autopsy and Gross Pathology questions

Keep practicing

More Autopsy and Gross Pathology questions