Respiratory Conditions · USMLE Step 1

A patient with asthma develops elevated eosinophils. Which protein is released by eosinophils that damages epithelial cells?

  1. Myeloperoxidase
  2. Major basic protein
  3. Elastase
  4. Histamine
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Correct answer: Major basic protein

Major basic protein from eosinophils damages airway epithelium in atopic asthma. It contributes to airway inflammation.

Difficulty: Medium Question 19 of 20

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