Tissue types and function · USMLE Step 1

Which characteristic is typical of connective tissue but not epithelial tissue?

  1. Cells tightly packed with minimal extracellular space
  2. Abundant extracellular matrix of fibers and ground substance
  3. Lines internal body cavities and outer surfaces
  4. Cells anchored to an underlying basement membrane
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Correct answer: Abundant extracellular matrix of fibers and ground substance

Connective tissue is distinguished by abundant extracellular matrix (fibers like collagen or elastic fibers and ground substance) which provides support, binding, and structural integration — a feature not typical of epithelial tissue.

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