Mendelian inheritance · USMLE Step 1

A male has an X-linked dominant disorder. Which of his children are expected to inherit the condition?

  1. Only sons
  2. Only daughters
  3. Half of all children
  4. All children
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Correct answer: Only daughters

X-linked dominant disorders are transmitted from affected fathers to all daughters. Sons inherit the Y chromosome and therefore are not affected.

Difficulty: Medium Question 12 of 20

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