Transcription and Translation · USMLE Step 1

Which type of RNA is produced by RNA polymerase I in eukaryotic cells?

  1. mRNA (messenger transcripts)
  2. tRNA (transfer transcripts)
  3. Large-subunit ribosomal rRNA
  4. snRNA (spliceosomal RNAs)
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Correct answer: Large-subunit ribosomal rRNA

RNA polymerase I transcribes rRNA precursors (except 5S rRNA), including large-subunit rRNAs, in the nucleolus — supplying components for ribosome assembly.

Difficulty: Medium Question 15 of 22

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