A growth factor binds to its receptor on a target cell. Subsequently, the receptor dimerizes and phosphorylates itself. Which downstream effect is most consistent with this mechanism?
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Correct answer: A phosphorylation cascade that alters gene expression
Growth factor receptors are often RTKs; their autophosphorylation initiates kinase cascades (e.g. MAPK) that lead to changes in gene expression and cell behavior.
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