Control of respiration · Physiology

The Pre-Bötzinger complex is a crucial component of the respiratory control system. What is its specific role?

  1. It acts as the pacemaker for the respiratory rhythm
  2. It integrates signals from the stretch receptors
  3. It coordinates the transition between forced inspiration and forced expiration
  4. It functions as the primary oxygen sensor in the medulla
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Correct answer: It acts as the pacemaker for the respiratory rhythm

Located in the upper part of the ventral respiratory group, the Pre-Bötzinger complex contains spontaneously firing neurons. It is widely considered the primary site of respiratory rhythm generation in the brainstem.

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