Exercise physiology · Physiology

During intense anaerobic exercise, fatigue is most closely associated with the accumulation of:

  1. Carbon dioxide
  2. Lactic acid and hydrogen ions
  3. Creatinine
  4. Urea
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Correct answer: Lactic acid and hydrogen ions

Accumulation of lactic acid and hydrogen ions lowers intracellular pH, impairing enzyme activity and muscle contraction. This contributes significantly to fatigue during high-intensity exercise.

Difficulty: Medium Question 6 of 20

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