Acid-base balance · Physiology

The primary buffer system in extracellular fluid is the:

  1. Phosphate buffer system
  2. Plasma protein buffer system
  3. Intracellular hemoglobin buffer system
  4. Bicarbonate buffer system
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Correct answer: Bicarbonate buffer system

The bicarbonate buffer system is the most important extracellular buffer. It works in conjunction with the lungs and kidneys to regulate pH.

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