Enzymes and Digestion of Carbs, Proteins, Fats · Physiology

The digestion of proteins does not end at the brush border. Which of the following is true regarding the final stages of protein digestion?

  1. Only free amino acids can be absorbed into the enterocyte
  2. Dipeptides and tripeptides are hydrolyzed inside the enterocyte
  3. Proteins are fully digested to amino acids in the stomach lumen
  4. Enterocytes lack any intracellular peptidase activity
Show answer and explanation

Correct answer: Dipeptides and tripeptides are hydrolyzed inside the enterocyte

While many amino acids are absorbed as singles, a significant portion of protein is absorbed as dipeptides and tripeptides. Once inside the enterocyte, cytosolic peptidases complete the digestion into free amino acids before they enter the blood.

Difficulty: Medium Question 31 of 40

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