Pancreatic lipase is the most important enzyme for fat digestion. What is the effect of the drug Orlistat on this process?
Show answer and explanation
Correct answer: It covalently binds to and inhibits pancreatic lipase, blocking fat absorption
Orlistat is a pharmacological inhibitor of gastric and pancreatic lipases. By preventing the breakdown of triglycerides into absorbable fatty acids, it reduces the total caloric intake from dietary fats, often used in weight management.
Practice all 40 Enzymes and Digestion of Carbs, Proteins, Fats questions
Keep practicing
More Enzymes and Digestion of Carbs, Proteins, Fats questions
- Which enzyme initiates carbohydrate digestion in the oral cavity?
- Which enzyme is responsible for protein digestion in the stomach?
- Which pancreatic enzyme digests triglycerides?
- Which substance is essential for efficient fat digestion?
- Which enzyme converts starch into maltose in the small intestine?
- Which brush border enzyme splits lactose into glucose and galactose?