Congenital hypothyroidism (Cretinism) leads to profound intellectual disability and stunted growth because thyroid hormones are essential for:
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Correct answer: Development of the CNS and myelination
Thyroid hormones are critical during the perinatal period for brain development, including dendrite branching and myelin formation. Without early replacement therapy, the damage to the central nervous system is irreversible.
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More Pituitary and Thyroid Physiology questions
- Which pituitary hormone is essential for postnatal growth and metabolism?
- Which thyroid hormone is present in the highest concentration in the circulation?
- Which pituitary hormone directly stimulates thyroid hormone synthesis and release?
- Which hormone inhibits thyroid-stimulating hormone release from the pituitary?
- Which pituitary hormone is primarily responsible for milk ejection?
- Which thyroid hormone has the highest biological activity at the cellular level?