Pharmacovigilance · Pharmacology

Pharmacovigilance activities are most crucial after marketing because:

  1. Drugs are cheaper after approval
  2. Clinical trials involve limited populations
  3. All ADRs are fully known and documented before approval
  4. Animal studies are discontinued
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Correct answer: Clinical trials involve limited populations

Clinical trials often involve limited sample sizes and selected populations. Rare or long-term adverse effects may only become apparent after widespread use in diverse patient groups.

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