Anticoagulants · Pharmacology

Which anticoagulant is most likely to cause osteoporosis during long-term therapy?

  1. Warfarin sodium
  2. Unfractionated Heparin
  3. Apixaban
  4. Dabigatran etexilate
Show answer and explanation

Correct answer: Unfractionated Heparin

Long-term use of heparin (especially UFH) is associated with decreased bone density and osteoporosis. This is thought to be due to increased osteoclast activity and decreased osteoblast formation.

Difficulty: Medium Question 16 of 20

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