Absolute bioavailability is calculated by comparing a drug administered orally with which route?
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Correct answer: Intravenous administration
Absolute bioavailability compares the systemic availability of a drug after non-intravenous administration to that after intravenous administration. IV dosing is considered the reference with 100% availability.
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More Bioavailability questions
- Which factor related to drug formulation can influence bioavailability?
- Which physiological factor may significantly affect oral drug bioavailability?
- Which property of a drug strongly influences its ability to cross biological membranes and affect bioavailability?
- Which site in the gastrointestinal tract is primarily responsible for drug absorption affecting bioavailability?
- Which phenomenon refers to the metabolic breakdown of a drug before it reaches systemic circulation?
- Which dosage form generally has higher bioavailability than tablets?